Cocaine
Cocaine is a powerful stimulant with high addiction potential and significant cardiovascular risk. Fentanyl contamination has increased dramatically — test every batch. The short duration drives compulsive redosing, which is where most harm occurs.
key risks
- Cardiovascular: significantly raises heart rate and blood pressure — most dangerous for people with heart conditions
- Fentanyl contamination: increasingly common in cocaine supply — always use a fentanyl test strip
- Levamisole: veterinary antibiotic found in most cocaine supplies, damages immune system with long-term use
- Addiction: high addiction potential — short duration creates strong urge to redose
- Cocaethylene: cocaine + alcohol forms a more toxic compound in the liver — responsible for many deaths
- Nasal damage: daily use causes progressive septum damage and nasal collapse
safer use
- Test with a fentanyl strip before every use — dissolve a small amount in water, dip the strip
- Use your own equipment — sharing increases hepatitis C risk
- Alternate nostrils and rinse with saline after use
- Set a limit before you start — compulsive redosing is the main harm pattern
- Never use alone — cardiovascular events can happen without warning
- Avoid combining with alcohol — the cocaethylene combination significantly increases cardiac risk
- Take breaks from dancing — overheating and dehydration compound cardiovascular strain
dangerous combinations
- Alcohol: forms cocaethylene, more toxic than either alone — avoid
- Other stimulants: additive cardiovascular strain — dangerous
- MAOIs: severe hypertensive crisis — life-threatening
- Heroin/opioids: "speedball" — masks warning signs of overdose from both substances
Ask Psychnosis about cocaine harm reduction, combinations, or what to do if something goes wrong.
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harm reduction reference only · not medical advice · psychnosis.org