MDMA
MDMA (3,4-methylenedioxymethamphetamine)

class Empathogen-entactogen
duration 3–6 hours
onset 30–90 minutes

MDMA is a synthetic drug that acts as a stimulant and psychedelic, producing an energising effect, distortions in time and perception, and enhanced enjoyment of sensory experiences. It increases serotonin, dopamine, and norepinephrine release.

effects

harm reduction

combination safety

Alcohol
increases dehydration and neurotoxicity
Cannabis
amplifies anxiety and heart rate
Cocaine
extreme cardiovascular strain
MAOIs
life-threatening serotonin syndrome

external sources

erowid ↗ psychonautwiki ↗ tripsit ↗ dancesafe ↗

related substances

LSDKetaminePsilocybinCocaine

Ask the Psychnosis AI anything about MDMA — effects, dosages, harm reduction, combinations, experiences, pharmacology.

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This information is for harm reduction purposes only. Always research substances thoroughly before use. Psychnosis does not encourage drug use. If you are struggling with substance use, please seek professional support.